“In the future it could be used as a non-invasive biomarker for the early activation of immune cells such as astrocytes in the central nervous system, which can be valuable to the development of new drugs and to the diagnostics of cognitive diseases.”
The research team searched for biomarkers in the blood of patients with a rare and inherited form of Alzheimer’s, where those who have a parent with the disease have a 50 percent chance of developing it.
They analysed 164 blood plasma samples from 33 mutation carriers, and 42 relatives without the inherited chance of getting Alzheimer’s taken between 1994 and 2018.
The findings revealed distinct changes of several blood protein concentrations in the mutation carriers.
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