Lung cancer: Symptoms may include knee pain

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These symptoms are sometimes seen in large-cell lung cancer, which comprises about five to 10 percent of all lung cancer.

“It is a diagnosis of exclusion, as it is often the diagnosis in which a lung malignancy does not show characteristics of smell cell, squamous cell, or adenocarcinoma,” explains the scientists at the Archive of Proceedings of Baylor University Medical Center.

“Most cases of synovial metastasis, specifically of the knee joint, from a lung primary demonstrated adenocarcinoma features […] followed by squamous cell carcinoma features.

“Unfortunately, all synovial metastasis carries with it a dreadful prognosis. Average survival after discovery is five months.”

READ MORE: Cancer symptoms are changing and two signs are becoming more common

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