Dementia: The ‘subtle indications’ of Alzheimer’s that can emerge almost two decades early

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“These associations were consistently larger among European Americans than among African Americans.

“Performance on individual cognitive tests of episodic memory, executive function, and global cognition also significantly predicted the development of AD dementia, with associations exhibiting a similar trend over 18 years.”

It concludes: “Our findings suggest that cognitive impairment may manifest in the preclinical phase of AD dementia substantially earlier than previously established.”

“Our results indicate that performance on a brief cognitive battery and on the cognitive domains measured by individual tests in the battery differs substantially between those who will subsequently develop clinically evident AD dementia and those who will not up to 18 years before diagnosis in a biracial population sample.

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