Furthermore, the researchers found that supplementing with vitamin B12 and folic acid increased the levels of syntaxin 17 in the liver and restored its role.
Plus, it also slowed NASH progression and reversed liver inflammation and fibrosis, which is the third stage of NAFLD.
Study co-author Dr Brijesh Singh said: “Our findings are both exciting and important because they suggest that a relatively inexpensive therapy, vitamin B12 and folic acid, could be used to prevent and/or delay the progression of NASH.
“Additionally, serum and hepatic homocysteine levels could serve as a biomarker for NASH severity.”
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