When receiving a booster vaccine, not everyone who is given Pfizer will have had the same vaccine for their two previous doses.
Moderna and Pfizer-BioNTech are the leading booster vaccinations used in the UK, which means those who have previously had the other authorised vaccines – such as AstraZeneca or Moderna, could receive the Pfizer booster.
Analysis by the ZOE Covid study found that: “For contributors who got three Pfizer doses, slightly fewer people reported systemic after effects after their booster (13.1 percent) compared to after their second dose (19.2 percent), and were also less likely to have local effects third time around.”
Data from ZOE also found people getting ‘mix and match’ vaccines were 1.5 times more likely to have systemic after-effects following their booster, particularly if they had a Moderna booster after two Pfizer or AstraZeneca vaccines.
While each person’s experience of the Pfizer booster will be different, there are a few common symptoms which are known to affect around one in 10 patients.